Rita Yen-Hua Huang, PhD
|
|
Job Title: |
Director Distinguished Professor |
Education: | PhD National Taiwan University, Biochemistry |
Specialty & Expertise: | Microenvironment signal regulatory mechanism of Pluripotent stem cells and cancer stem cells, Germline stem cells, Liver cancer stem cells, Endometrial cancer stem cells |
Email: | rita1204@tmu.edu.tw |
Phone: | (+886)2-2736-1661 Ext 3150 |
Web Page: | Rita Lab Rita Blog |
Professional Experience
2010~now |
Deputy Director,
Center
for
Teeth
Bank and
Dental
Stem
Cell
Biotechnology,
Taipei
Medical
University,
Taipei,
Taiwan |
2011~2013 |
Secretary
General,
Taiwan
Society
for Stem
Cell
Research
(TSSCR),
Taiwan |
2014~now |
Professor
and
Director,
Department
of
Biochemistry
and
Molecular
Cell
Biology,Graduate
Institute
of
Medical
Sciences,
College
of
Medicine,
Taipei
Medical
University,
Taipei,
Taiwan |
2015~now |
Director,
TMU
Center
for Cell
Therapy
and
Regeneration
Medicine,
Taipei
Medical
University,
Taipei,
Taiwan |
2016~now |
Director,
TMU GTP
Laboratory,
Taipei
Medical
University,
Taipei,
Taiwan
|
| Research Interests | Honor | Grant | Publication |
Honor:(more...)
2016 |
2016 The Outstanding
Basic Research Award for
Cancer Medicine of Dr. Da-Cheng
Tung, The Chinese Oncology
Society (COS)
|
2015 |
2015 The International Top
Journal Research Award of
Taipei Medical University |
2014 |
2014 The Prize Poster Award,
“Insulin-like
Growth Factor I Stimulates
the Expressions of HIF-2α
and Oct-4 Requiring α6
Integrin in Mouse Germline
Stem Cells”,
2014 Taiwan Society For Stem
Cell Research (2014 TSSCR),
Taipei, Taiwan
2014 Ministry of Science and
Technology 103 annual
subsidy college special
award of outstanding talents |
2013 |
2013 Faculty Award of Taipei
Medical University in
Excellence of Teaching,
Administration, and
Research.
2013 The First Prize Oral
Award,
“IGF-1R-HIF-2a
Signal Loop Supports the
2013 The Prize Poster Award,
“Interleukin-6
Regulates Stemness
Expression and Early
Recurrence of HBV-related
Hepatocellular Carcinoma via
IGF-IR Activation”
& “Role
of IGF-1R Signaling in Oct-4
Maintenance of Alkaline
Phosphatase Positive
Germline Stem Cells”.
2013 The 27th Joint Annual
Conference of Biomedical
Sciences, Taipei, Taiwan.
2013 The Excellent Research
Paper Award,”
Interleukin-6 Regulates
Stemness Expression and
Early Recurrence of
HBV-related Hepatocellular
Carcinoma via IGF-IR
Activation “.
2013 Teachers and Students
Joint Academic Research
Symposium,Taipei Medical
University, Taipei, Taiwan
2013 The Prize Poster Award,
“
IGF-IR-HIF-2a Signaling Loop
Supports the Cell
Proliferation and Oct4
Maintenance of Alkaline
Phosphatase Positive Mouse
Germline Stem Cell. 2013
Taiwan Society for Stem Cell
Research (2013 TSSCR),
Taipei, Taiwan.
2013 The Prize Poster Award,
“ HBx
Stimulates the Expression of
Stemness-related Properties
through SENP1in HBV-related
Hepatocellular Carcinomas.
2013 Taiwan Society for Stem
Cell Research (2013 TSSCR),
Taipei, Taiwan.
2013 The Best Teacher Award,
School of Medicine, Taipei
Medical University, Taipei,
Taiwan |
2012 |
2012 The Prize Poster Award,
“ IL-6
stimulates stemness
properties and early
recurrence of HCC through
IGF-IR activation. 2012
Taiwan Society for Stem Cell
Research (2012 TSSCR),
Taipei, Taiwan.
1011 Teaching excellence
(Biochemistry)
1012 Teaching excellence
(Biochemistry Experiment) |
2011 |
2011 The Second Prize Oral
Award,
“ SENP1
Regulates OCT4 Under
Hypoxia: Effect of
Sumoylation on Protein
Stability and Drug
Susceptibility of Human
Pluripotent Germ Cell Tumors”
2011 International Symposium
on Recent Advances in
Pluripotent Stem Cells &7th
Annual Meeting of Taiwan
Society for Stem Cell
Research (2011 TSSCR). |
2010 |
2010 The most excellent
teacher of TMU |
2009 |
2009 Prize Award, The 7th
Conference of the Pacific
Rim Society for Fertility
and Sterility (PRSFS 2009)
– “
Hypoxia Stress Enhances the
IGF-1 Signaling in
Pluripotent Mouse Germline
Stem Cells”
, Taipei, Taiwan (2009
PRSFS) |
American Journal of Physiology Endocrinology and Metabolism
Electronic Journal of Biotechnology
Fertility & Sterility
BMC Developmental Biology
Adaptive
Medicine
Grant Number
Project Topic
Sponsor
NTD
Period from
to
MOST105-2628-B-
038-008MY3(1-3)
Role of HBx and
androgen receptor in
regulating SENP1/stemessrelated
Ministry of
Science and Technology
1,860,000
2016/8/1
2017/7/31
MOST104-2321-
B-038-003
Differential
machinery of pluripotency
regulation in stem cells in
embryonic stage and somatic
cancers and its clinical
implications in human
diseases --crosstalk among
niche growth factor/cytokine
signaling, extracellular
matrix, and epigenetic
networks. (2/2)
Ministry of
Science and Technology
2,800,000
2015/10/1
2016/9/30
NSC102-2628-B-
038-008-MY3(3-3)
Role of HBX and
IL-6 in regulating SENP1 /
stemness properties of
HBV-related HCC under
hypoxia and its clinical
implication
Ministry of
Science and Technology
1,660,000
2015/8/1
2016/7/31
TMU-T104-06
幹細胞基礎研究與前臨床動物試驗
Taipei Medical
University
1,200,000
2015/8/1
2016/7/31
104TMU-TMUH-04
Igf-1r—Cxcr4
signal loop regulates cell
migration through Hif-2α
in mouse germline stem cells
under hypoxia
TMU Hospital
500,000
2015/6/1
2016/5/31
A-104-011
StemBios幹細胞研究計畫
StemBios
Technologies, Inc.
8,000,000
2014/12/15
2017/12/14
MOST103-2321-B-
038-011
Differential
machinery of pluripotency
regulation in stem cells in
embryonic stage and somatic
cancers and its clinical
implications in human
diseases --crosstalk among
niche growth
StemBios
Technologies, Inc.
2,800,000
2014/10/1
2015/9/30
A-103-057
StemBios幹細胞混和複合式材料於皮膚傷口修復能力之動物模式評估研究計畫
StemBios
Technologies, Inc.
3,000,000
2014/9/1
2015/8/31
NSC102-2628-B-
038- 008-MY3(2-3)
Role of HBX and
IL-6 in regulating SENP1 /
stemness properties of
HBV-related HCC under
hypoxia and its clinical
implication
Ministry of
Science and Technology
1,660,000
2014/8/1
2015/7/31
103TMU-TMUH-05
The mechanism of
extracellular matrix (laminin)
and insulin-like growth
factor-1(IGF-1) in
self-renewal signaling of
mouse germline stem cells
TMU Hospital
450,000
2014/6/1
2015/5/31
103TMU-WFH-01-2
Effect of Au nano
particle-teated (Au-NT)
water in reducing plasma
cholesterol using animal
model and its clinical
implications in
atherosclerosisi
TMU/Wan Fang
Hospital
500,000
2014/6/1
2015/5/31
NSC 102-2321-B-
038-001
Niche signaling
networks in self-renewal and
migration of pluripotent
germline stem cells and its
implication for germline
differentiation in human
pluripotent stem cells.
(3/3)
Ministry of
Science and Technology
2,801,000
2013/10/1
2014/9/30
NSC
102-2628-B-038- 008-MY3(1-3)
Role of HBX and
IL-6 in regulating SENP1 /
stemness properties of
HBV-related HCC under
hypoxia and its clinical
implication
Ministry of
Science and Technology
1,660,000
2013/8/1
2014/7/31
A-102-023
StemBios幹細胞於異體移植之動物模式前臨床試驗安全性與功能性評估
StemBios
Technologies, Inc.
2,000,000
2013/6/1
2014/5/31
102TMU-TMUH-13
The role of TGF-B1
in OCT4 expression and
epithelial-mesenchymal
transition (EMT) in
endometriosis
TMU/TMU Hospital
450,000
2013/6/1
2014/5/31
NSC 101-2321-B-
038-001
Niche signaling
networks in self-renewal and
migration of pluripotent
germline stem cells and its
implication for germline
differentiation in human
pluripotent stem cells.
(2/3)
Ministry of
Science and Technology
2,818,000
2012/10/1
2013/9/30
NSC 99-2628-B-
038- 009-MY3(3-3)
Circuits of IGF-1R
and Niche Signaling
(Hypoxia/Inflammation) in
Stem Cell Transformation and
its Clinical Implication of
Molecular Target Therapy
(Model of Germline Stem
Cells)
Ministry of
Science and Technology
1,340,000
2012/8/1
2013/7/31
NSC 100-2321-B-
038-003
Niche signaling
networks in self-renewal and
migration of pluripotent
germline stem cells and its
implication for germline
differentiation in human
pluripotent stem cells.
(1/3)
Ministry of
Science and Technology
2,803,000
2011/10/1
2012/9/30
NSC 99-2628-B-038-
009- MY3(2-3)
Circuits of IGF-1R
and Niche Signaling
(Hypoxia/Inflammation) in
Stem Cell Transformation and
its Clinical Implication of
Molecular Target Therapy
(Model of Germline Stem
Cells)
Ministry of
Science and Technology
1,340,000
2011/8/1
2012/7/31
100TMU-TMUH-13
Role of
inflammatory cytokines and
endometrium stem cells in
endomatriosis and clincial
implication
TMU/TMU Hospital
500,000
2011/4/1
2012/3/31
NSC 99-3111-B-
038-001
Characterization
of the
self-renewal/reprogramming
factors of human/mouse germ
line stem cells in
Ministry of
Science and Technology
2,000,000
2010/12/1
2011/9/30
NSC 99-2628-B-
038- 009-MY3(1-3)
serum-free culture
system and its induction
effect on human embryonic
stem cells to sperm
(Extension proposal)
Ministry of
Science and Technology
1,300,000
2010/8/1
2011/7/31
NSC
98-3111-B-038-001
Characterization
of the
self-renewal/reprogramming
factors of human/mouse germ
line stem cells in
Ministry of
Science and Technology
2,617,000
2009/12/1
2010/11/30
Journal Review Committee:
Grant
(more...)
properties in HBV-related
HCC and its clinical impact
factor/cytokine signaling,
extracellular matrix, and
epigenetic networks. (1/2)
Department of
Biochemistry and Molecular Cell Biology
| School
of Medicine
| TMU